List of available International Chemical Reference Substances
International Chemical Reference Substances (ICRS) are established on the advice of the WHO Expert Committee on Specifications for Pharmaceutical Preparations. They are supplied primarily for use in physical and chemical tests and assays described in the specifications for quality control of drugs published in The international pharmacopoeia or proposed in draft monographs. The ICRS are mainly intended to be used as primary standards to calibrate secondary standards.
Directions for use, and the analytical data required for the use described in the relevant specifications of The international pharmacopoeia, are given in the certificates enclosed with the substances when distributed. More detailed analytical reports on the substances may be obtained from the WHO Collaborating Centre for Chemical Reference Substances.
ICRS may also be used in tests and assays not described in The international pharmacopoeia. However, the responsibility for assessing the suitability of the substances then rests with the user or with the pharmacopoeia commission or other authority that has prescribed this use.
See pdf below for complete details:
WHO TRS (Technical Report Series) 902, 2002 Annex 1: pdf
